Researchers suspend, image single DNA molecules

(PhysOrg.com) -- Studying chemical modifications in the chromosomes of cells is akin to searching for changes in coiled spaghetti. Scientists at Cornell have figured out how to stretch out tangled strands of DNA from chromosomes, ...

'Soft' CRISPR may offer a new fix for genetic defects

Curing debilitating genetic diseases is one of the great challenges of modern medicine. During the past decade, development of CRISPR technologies and advancements in genetics research brought new hope for patients and their ...

From fish to man: Research reveals how fins became legs

Vertebrates' transition to living on land, instead of only in water, represented a major event in the history of life. Now, researchers reporting in the December issue of the journal Developmental Cell provide new evidence ...

Study offers insight into the origin of the genetic code

An analysis of enzymes that load amino acids onto transfer RNAs—an operation at the heart of protein translation—offers new insights into the evolutionary origins of the modern genetic code, researchers report. Their ...

Getting a tighter grip on cell division

(PhysOrg.com) -- The dance of cell division is carefully choreographed and has little room for error. Paired genetic information is lined up in the middle of the cell in the form of chromosomes. The chromosomes must then ...

Researchers build most complex synthetic biology circuit yet

Using genes as interchangeable parts, synthetic biologists design cellular circuits that can perform new functions, such as sensing environmental conditions. However, the complexity that can be achieved in such circuits has ...

Mutation breaks HIV's resistance to drugs

The human immunodeficiency virus (HIV) can contain dozens of different mutations, called polymorphisms. In a recent study an international team of researchers, including MU scientists, found that one of those mutations, called ...

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