Crop protection: Biohacking against fungal attacks

Harmful fungi cause enormous agricultural losses. Conventional techniques for combating them involve the use of poisonous fungicides. Researchers at Karlsruhe Institute of Technology (KIT), working with partners from Germany, ...

Artificial enzyme can activate a gene switch

Complex reaction cascades can be triggered in artificial molecular systems: Swiss scientists have constructed an enzyme than can penetrate a mammalian cell and accelerate the release of a hormone. This then activates a gene ...

Uncovering a reversible master switch for development

In a paper published in Genes & Development, BWH principal investigator Mitzi Kuroda, PhD, and her team identified a reversible "master switch" on most developmental genes. The team unearthed this biological insight through ...

Controlling gene activity in human development

Researchers at the Babraham Institute have revealed a new understanding of the molecular switches that control gene activity in human embryonic stem cells. This insight provides new avenues for improving the efficiency of ...

Protein paves the way for correct stem cell differentiation

A single embryonic stem cell can develop into more than 200 specialized cell types that make up our body. This maturation process is called differentiation and is tightly regulated. If the regulation is lost, specialized ...

Reproduction and life span are intertwined

The gonad is well known to be important for reproduction but also affects animal life span. Removal of germ cells – the sperm and egg producing cells – increases longevity of the roundworm Caenorhabditis elegans. However, ...

Judging DNA by its cover

Stem cells hold great promise for the medicine of the future, but they can also be a cause of disease. When these self-renewing, unspecialized cells fail to differentiate into diverse cell types, they can start dividing uncontrollably, ...

Chasing EHEC with the computer

Just a few genes make enterohaemorrhagic E. coli (EHEC) extremely dangerous to humans. If it were not for these genes, EHEC would hardly differ from harmless enteric bacteria. Bioinformatics scientists from the Saarbrücken ...

NC State develops more precise genetic 'off switches'

Researchers at North Carolina State University have found a way to "cage" genetic off switches in such a way that they can be activated when exposed to UV light. Their technology gives scientists a more precise way to control ...

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