A genome by itself is like a recipe without a chef—full of important information, but in need of interpretation. So, even though we have sequenced genomes of our nearest extinct relatives—the Neanderthals and the Denisovans—there ...
Molecular & Computational biology
Apr 26, 2021
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104
New insights into a little-understood DNA structure could provide the basis for new cancer therapies.
Biotechnology
Mar 18, 2021
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54
Genome analysis can provide information on genes and their location on a strand of DNA, but such analysis reveals little about their spatial location in relation to one another within chromosomes—the highly complex, three-dimensional ...
Cell & Microbiology
Jan 14, 2021
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70
Understanding how genes work and how they interact with one another is a major goal of biology. This poses huge challenges in terms of both methods and the sheer numbers of experiments required. Recent advances have transformed ...
Biotechnology
Dec 10, 2020
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29
Thousands of years ago, people in South America began domesticating Solanum pimpinellifolium, a weedy plant with small, intensely flavored fruit. Over time, the plant evolved into S. lycopersicum—the modern cultivated tomato.
Ecology
Dec 1, 2020
1
805
The addition and removal of methyl groups on DNA plays an important role in gene regulation. In order to study these mechanisms more precisely, a German team has developed a new method by which specific methylation sites ...
Biochemistry
Nov 24, 2020
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19
A new strategy for treating a variety of diseases known as RNA-repeat expansion disorders, which affect millions of people, has shown promise in proof-of-principle tests conducted by scientists at Scripps Research.
Biochemistry
Nov 6, 2020
0
138
Researchers in Dana-Farber's cBio Center have now demonstrated a powerful 'experimental evolution' method to discover details of protein shape and function, and the method may find uses across a very broad spectrum of biomedical ...
Cell & Microbiology
Dec 11, 2019
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91
The DNA of a single cell is two to three meters long end-to-end. To fit in the nucleus and function correctly, DNA is packaged around specialized proteins. These DNA-protein complexes are called nucleosomes, and they are ...
Biotechnology
Nov 21, 2019
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126
Here's a discovery well worth toasting: A research team led by Professor Brandon Gaut with the University of California, Irvine and Professor Dario Cantu with the University of California, Davis has deciphered the genome ...
Plants & Animals
Sep 10, 2019
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