Understanding how genes work and how they interact with one another is a major goal of biology. This poses huge challenges in terms of both methods and the sheer numbers of experiments required. Recent advances have transformed ...
Biotechnology
Dec 10, 2020
0
29
Thousands of years ago, people in South America began domesticating Solanum pimpinellifolium, a weedy plant with small, intensely flavored fruit. Over time, the plant evolved into S. lycopersicum—the modern cultivated tomato.
Ecology
Dec 1, 2020
1
805
The addition and removal of methyl groups on DNA plays an important role in gene regulation. In order to study these mechanisms more precisely, a German team has developed a new method by which specific methylation sites ...
Biochemistry
Nov 24, 2020
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19
A new strategy for treating a variety of diseases known as RNA-repeat expansion disorders, which affect millions of people, has shown promise in proof-of-principle tests conducted by scientists at Scripps Research.
Biochemistry
Nov 6, 2020
0
138
In eukaryotic cells, the genomic DNA is hierarchically packaged by histones into chromatin. Chromatin structure and its plasticity play an important role in the activation and silencing of gene transcription, and determine ...
Cell & Microbiology
Jul 29, 2020
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18
What is and is not possible for natural evolution may be explained using models and calculations from theoretical physics, say researchers in Japan.
General Physics
May 29, 2020
0
16
For the last eight years, the Genome Aggregation Database (gnomAD) Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more ...
Biotechnology
May 28, 2020
0
8
The genetic information within cells makes individuals unique. The cell nucleus has a complex structure that harbors this genetic information. The main component of the nucleus is chromatin, an intercalated pool of genes ...
Biotechnology
May 12, 2020
0
6
Researchers in Dana-Farber's cBio Center have now demonstrated a powerful 'experimental evolution' method to discover details of protein shape and function, and the method may find uses across a very broad spectrum of biomedical ...
Cell & Microbiology
Dec 11, 2019
0
91
It's long been known that the proteins that package DNA, like students at a high school dance, require a chaperone. But what exactly that guardian looks and acts like has been a mystery—until now.
Molecular & Computational biology
Nov 27, 2019
0
378
