A new method that can induce interactions between specifically chosen locations on the genome allows researchers to begin to identify the causal relationship between three-dimensional chromosome structure and genome function. ...
Cell & Microbiology
Feb 18, 2022
0
50
Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)." These are ...
Cell & Microbiology
Jan 24, 2022
0
52
A new paper in Genome Biology and Evolution maps out for the first time how Hydra, which are a group of small aquatic animals, can regenerate their own heads by changing the way that their genes are regulated, known as epigenetics.
Evolution
Dec 8, 2021
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31
Proteins known as transcription factors act as switches that regulate the expression of nearby genes, but the identity of some of these genetic levers has so far remained mysterious. Now, researchers from the Schübeler group ...
Biotechnology
Jul 8, 2021
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30
Scientists know that developing cells in a healthy embryo will transform into a variety of cell types that will make up the different organ systems in the human body, a process known as cell differentiation. But they don't ...
Cell & Microbiology
Jun 14, 2021
0
11
During development, scores of molecular signals prod cells to take on specialized identities and functions. In response to some of these signals, the cellular machinery awakens specific genes called 'immediate early genes' ...
Molecular & Computational biology
Feb 19, 2021
0
89
Pathogenic bacteria in humans are developing resistance to antibiotics much faster than expected. Now, computational research at Chalmers University of Technology, Sweden, shows that one reason could be significant genetic ...
Cell & Microbiology
Jan 21, 2021
0
120
The generation of species-specific singing in songbirds is associated with species-specific patterns of gene activity in brain regions called song nuclei, according to a study published November 12 in the open-access journal ...
Plants & Animals
Nov 12, 2019
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21
How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...
Molecular & Computational biology
May 2, 2019
0
91
Species often experience a genetic bottleneck that diminishes genetic variation after speciation or introduction into a new area. Though bottlenecks in population size always reduce fitness and evolutionary potential, introduced ...
Plants & Animals
Mar 19, 2019
0
75
