Pulling the strings of our genetic puppetmasters: Engineers gain control of gene activity
Duke researchers have developed a new method to precisely control when genes are turned on and active.
Duke researchers have developed a new method to precisely control when genes are turned on and active.
Biotechnology
Apr 6, 2015
6
735
Embryonic development involves the tightly coordinated activity of thousands of genes, each switched on at a specific time and place in the growing organism under the control of regulatory DNA sequences called promoters. ...
Biotechnology
Nov 1, 2013
0
0
(Phys.org) —A researcher from The University of Queensland, has conducted the world's first pineapple microarray to gain a better understanding of tropical fruit development at the molecular level.
Cell & Microbiology
Sep 2, 2013
0
0
When egg and sperm combine, the new embryo bustles with activity. Its cells multiply so rapidly they largely ignore their DNA, other than to copy it and to read just a few essential genes. The embryonic cells mainly rely ...
Biotechnology
Aug 13, 2013
1
0
Whitehead Institute researchers have determined that DNA transcription, the process that produces messenger RNA (mRNA) templates used in protein production, also runs in the opposite direction along the DNA to create corresponding ...
Cell & Microbiology
Feb 4, 2013
0
0
(Phys.org)—In certain toy racecar tracks, sneaky players can flip a switch, trapping their opponents' vehicles in a loop of track. Cells employ a less subtle approach: they change the track's layout. In a study published ...
Cell & Microbiology
Sep 28, 2012
0
0
Mammalian cells pack their genome into a highly organized three-dimensional structure, in which the thread-like DNA is wrapped tightly around spool-like proteins. This structure, known as chromatin, plays an important role ...
Cell & Microbiology
Jul 18, 2012
0
0
In exploring how proteins interact with crucial DNA sequences to regulate gene activity, researchers have shed light on key biological events that may eventually be manipulated to provide new disease treatments.
Cell & Microbiology
Jun 7, 2012
0
0
The problem in biology of how to identify the promoters of olfactory receptor genes (>1000 genes) has remained unsolved due to the difficulty of purifying sufficient material from the olfactory epithelium. Researchers at ...
Biotechnology
Jan 5, 2012
0
0
(PhysOrg.com) -- A team of Harvard Stem Cell Institute (HSCI) researchers has made a major advance toward producing induced pluripotent stem cells, or iPS cells, that are safe enough to use in treating diseases in patients.
Cell & Microbiology
Oct 8, 2009
0
0