IMP scientists from the lab of Alexander Stark show why certain activators—enhancers or cofactor proteins—activate specific promoters. The findings, which are now reported in the journal Nature, could have implications ...
Biotechnology
May 16, 2019
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83
It was long thought that DNA, together with the genes encoded in it, determined genetic destiny. But equally important is coordinating when genes are turned on and off. In fact, the regulation of gene expression defines life ...
Evolution
Sep 11, 2018
1
15
While aging is familiar to all of us, exactly how it occurs on a molecular basis has been an area of intense study and interest. We take it for granted that different species age at different rates, yet we do not have a good ...
Biotechnology
Apr 30, 2018
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137
Rice University scientists have created a toolkit for synthetic biologists who need to precisely tune the input and output levels of genetic circuits.
Cell & Microbiology
Jan 11, 2018
0
43
A team of University of Delaware researchers is opening wider the door for those who study the vast world of microbes. A paper published in Nature Communications on May 6 describes a new technique they developed for examining ...
Cell & Microbiology
May 7, 2015
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23
When egg and sperm combine, the new embryo bustles with activity. Its cells multiply so rapidly they largely ignore their DNA, other than to copy it and to read just a few essential genes. The embryonic cells mainly rely ...
Biotechnology
Aug 13, 2013
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0
Whitehead Institute researchers have determined that DNA transcription, the process that produces messenger RNA (mRNA) templates used in protein production, also runs in the opposite direction along the DNA to create corresponding ...
Cell & Microbiology
Feb 4, 2013
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0
(Phys.org)—In certain toy racecar tracks, sneaky players can flip a switch, trapping their opponents' vehicles in a loop of track. Cells employ a less subtle approach: they change the track's layout. In a study published ...
Cell & Microbiology
Sep 28, 2012
0
0
In exploring how proteins interact with crucial DNA sequences to regulate gene activity, researchers have shed light on key biological events that may eventually be manipulated to provide new disease treatments.
Cell & Microbiology
Jun 7, 2012
0
0
In high-precision bioengineering and synthetic biology, the fine-tuning of gene expression at transcriptional and posttranscriptional levels is essential. This involves a detailed understanding and manipulation of promoters ...
Biotechnology
Dec 11, 2023
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1
