News tagged with gene activation

A knockout resource for mouse genetics

An international consortium of researchers report today in Nature that they have knocked out almost 40 per cent of the genes in the mouse genome. The completed resource will power studies of gene activity in models of human ...

dateJun 15, 2011 in Biotechnology
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Stem cells: Tuning the death sentence

In this week's issue of Science Signaling (22 January, 2013), Danen and colleagues of the Division of Toxicology of LACDR report novel insights into the question how stem cells decide to commit suicide when their DNA is damaged.

dateJan 23, 2013 in Cell & Microbiology
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Making and breaking heterochromatin

To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, known as heterochromatin. ...

dateSep 25, 2012 in Cell & Microbiology
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