Gip1 structure places G proteins in lockdown

Heterotrimeric G proteins are important in G protein-coupled receptor signaling, which plays many roles in the detection of various environmental stimuli, including hormones, neurotransmitters, light, smells, and chemical ...

Expanding the optogenetics toolkit

Controlling individual brain cells using light-sensitive proteins has proven to be a powerful tool for probing the brain's complexities. As this branch of neuroscience has expanded, so has the demand for a diverse palette ...

Tiny protein has big impact in times of stress

Ribosomes churn out proteins that carry out all of life's functions, but when missing a key and previously overlooked factor, they can break down in times of stress, Yale University scientists have discovered. 

Newly discovered cytoskeleton helps cancer cells survive

Researchers at Lund University in Sweden have discovered a cytoskeleton which provides the structure for mitochondria, the cell's energy producers. The skeleton is necessary for the function of the mitochondria, but the researchers ...

VOX pops cereal challenge

A popular technique for studying genes from different organisms plus a new carrier to transfer them to plants has yielded a powerful tool for understanding crops better.

Cellular 'garbage disposal' has another job

Johns Hopkins researchers have found that the cellular "garbage disposal," known to scientists as proteasomes, may not only be responsible for the removal of cellular waste, but actually work on some of the most important ...

Scientists see human immune response in the fruit fly

Washington State University researchers have seen how both humans and fruit flies deploy a protein that a plays a critical role in their immune responses to invading bacteria. The discovery gives scientists evolutionary insight ...

How to code a functional molecular machine

An international team has developed a model that simulates protein evolution. Starting from stiff, unfunctional proteins, the computer model shows how evolving protein components can work together to give rise to dynamic ...

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