Lab-made protein chomps co-factor like a big ol' gator
Proteins have the power to turbo-charge biochemical reactions inside the body.
Biochemistry
Sep 14, 2017
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Page 15 - News tagged with folding
Researchers shed further light onto zinc homeostasis in cells
A research group has unearthed how zinc transporter complexes regulate zinc ion (Zn2+) concentrations in different areas of the Golgi apparatus and revealed that this mechanism finely tunes the chaperone protein ERp44.
Cell & Microbiology
May 29, 2023
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42
Obesity: Reviving the promise of leptin
(PhysOrg.com) -- The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. But hopes dimmed when it ...
Jan 6, 2009
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New fluorophores could help fight cancer
Scientists from the Ural Federal University and the Ural Branch of the Russian Academy of Sciences have created new fluorescent chemical compounds (fluorophores) for photodynamic therapy of cancerous tumors, the latest method ...
Biochemistry
Jun 27, 2022
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PERK protein opens line of communication between inside and outside of the cell
PERK is known to detect protein folding errors in the cell. Researchers at the Laboratory of Cell Death Research & Therapy at KU Leuven (University of Leuven, Belgium) have now revealed a hidden perk: the protein also coordinates ...
Cell & Microbiology
Feb 23, 2017
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8
Influence of nanoparticles, surrounding ions on formation of β-sheet structure in amyloid β proteins
Protein function and activity are determined by both their assembly and secondary structure. Abnormalities related to either protein aggregation or secondary structure can lead to neurodegenerative diseases. In a new study, ...
Bio & Medicine
Jul 14, 2022
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Researchers visualize RNA architecture
Scientists at A*STAR's Genome Institute of Singapore (GIS) and the US-based Stanford University's School of Medicine have successfully produced one of the first ever genome-wide views of Ribonucleic acid (RNA) shape patterns ...
Cell & Microbiology
Feb 4, 2014
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0
Protein folding in times of oxygen deficiency
Proteins often consist of hundreds or thousands of individual parts—the amino acids. These are connected like the links of a chain. However, protein molecules would not be able to fulfill their task as a long filament flapping ...
Plants & Animals
Jul 12, 2022
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19
Using integrated manipulation and imaging to study the accelerated folding of proteins
Following a single protein inside the cavity of a GroEL chaperone for the first time, researchers at AMOLF led by professor Sander Tans discovered how protein folding can be accelerated. Amino acid chains are pulled inside ...
Biotechnology
Mar 8, 2022
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91
Unique high-throughput approach improves the design of new protein structures
Northwestern Medicine investigators have solved a challenging protein design puzzle using a unique high-throughput approach, according to a study published in Proceedings of the National Academy of Sciences.
Molecular & Computational biology
Oct 28, 2022
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