Related topics: influenza · swine flu · flu · influenza virus · virus

Uncovering the role of membrane sugars in flu infection

The flu virus relies on using human cells to reproduce and spread. But before it even gets to the cell surface, the virus must navigate the tall, dense forest of sugar-coated proteins on the cell surface known as the glycocalyx. ...

New pathogenic mechanism for influenza NS1 protein found

Influenza is a deadly virus, with about 290,000 to 650,000 deaths worldwide each year. When pandemics hit, the toll can soar: The Spanish flu of 1918 caused 40 million to 50 million deaths, the Asian flu of 1957 caused 2 ...

Egg-based flu vaccines: Not all they're cracked up to be?

Flu season is underway in the Northern Hemisphere, sickening millions of people and in rare cases, causing hospitalization or death. The best prevention is a flu shot, but it's not unusual for these vaccines to be less effective ...

What blocks bird flu in human cells?

Normally, bird flu viruses do not spread easily from person to person. But if this does happen, it could trigger a pandemic. Researchers from the MDC and RKI have now explained in the journal Nature Communications what makes ...

Fullerene compounds knock out virus infections like HIV and HSV

Scientists from the Skoltech Center for Energy Science and Technology and the Institute of Problems of Chemical Physics of RAS in collaboration with researchers from four other Russian and foreign research centers have discovered ...

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Orthomyxoviridae

Influenzavirus A Influenzavirus B Influenzavirus C Isavirus Thogotovirus

The Orthomyxoviridae (orthos, Greek for "straight"; myxa, Greek for "mucus") are a family of RNA viruses that includes five genera: Influenzavirus A, Influenzavirus B, Influenzavirus C, Isavirus and Thogotovirus. The first three genera contain viruses that cause influenza in vertebrates, including birds (see also avian influenza), humans, and other mammals. Isaviruses infect salmon; thogotoviruses infect vertebrates and invertebrates, such as mosquitoes and sea lice.

The three genera of Influenzavirus, which are identified by antigenic differences in their nucleoprotein and matrix protein infect vertebrates as follows:

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