Related topics: influenza · virus · flu · vaccine · flu virus

Snapshots of the flu virus replication machine in action

Researchers from EMBL Grenoble have, for the first time, observed different functional states of the influenza virus polymerase as it is actively transcribing. These results, published in Nature Structural & Molecular Biology, ...

Virulence factor of the influenza A virus mapped in real-time

The influenza A viruses, which are responsible for deadly pandemics in the past, still remain a major global public health problem today. Molecules known as virulence factors are produced by bacteria, viruses, and fungi to ...

Mechanism to form influenza A virus discovered

The influenza A virus is known to form new strains every year. These strains are the result of small variations occurring at the level of the genome, which cause the virus to change and become unfamiliar to the immune system. ...

Could dogs be the source of a new flu?

Results from a 10-year study suggest two strains of influenza that could mix and form a dangerous new strain of influenza spread by dogs.

Scientists discover a potential strategy to treat influenza A

A team of researchers from Scripps Research and Janssen Research & Development LLC has discovered an orally active small molecule that neutralizes influenza A group 1 viruses, the most common flu strains. Scientists uncovered ...

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Orthomyxoviridae

Influenzavirus A Influenzavirus B Influenzavirus C Isavirus Thogotovirus

The Orthomyxoviridae (orthos, Greek for "straight"; myxa, Greek for "mucus") are a family of RNA viruses that includes five genera: Influenzavirus A, Influenzavirus B, Influenzavirus C, Isavirus and Thogotovirus. The first three genera contain viruses that cause influenza in vertebrates, including birds (see also avian influenza), humans, and other mammals. Isaviruses infect salmon; thogotoviruses infect vertebrates and invertebrates, such as mosquitoes and sea lice.

The three genera of Influenzavirus, which are identified by antigenic differences in their nucleoprotein and matrix protein infect vertebrates as follows:

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