Related topics: influenza · virus · flu · vaccine · flu virus

Tracing and controlling high pathogenicity avian influenza

Since October 30, 2020, there have been over 30 recorded outbreaks of high pathogenicity avian influenza (HPAI) in domestic poultry and wild fowl in Japan. This outbreak was caused by the influenza A virus H5N8, a known High ...

New synthetic molecule can kill the flu virus

EPFL scientists have developed a synthetic molecule capable of killing the virus that causes influenza. They hope their discovery will lead to an effective drug treatment.

Structural clues for influenza virus assembly and disassembly

The influenza A virus is surrounded by a lipid bilayer that forms the outermost layer much like the plasma membranes on our own cells. Immediately under this lipid bilayer is a dense protein layer formed from M1 matrix protein. ...

Influenza virus-induced oxidized DNA activates inflammasomes

Both influenza virus M2, a proton-selective ion channel essential for efficient viral replication, and PB1-F2 protein, which localizes to the mitochondria and attenuates host antiviral immunity, are involved in the inflammatory ...

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Orthomyxoviridae

Influenzavirus A Influenzavirus B Influenzavirus C Isavirus Thogotovirus

The Orthomyxoviridae (orthos, Greek for "straight"; myxa, Greek for "mucus") are a family of RNA viruses that includes five genera: Influenzavirus A, Influenzavirus B, Influenzavirus C, Isavirus and Thogotovirus. The first three genera contain viruses that cause influenza in vertebrates, including birds (see also avian influenza), humans, and other mammals. Isaviruses infect salmon; thogotoviruses infect vertebrates and invertebrates, such as mosquitoes and sea lice.

The three genera of Influenzavirus, which are identified by antigenic differences in their nucleoprotein and matrix protein infect vertebrates as follows:

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