Researchers have developed and demonstrated a new method for high-throughput single-cell sorting that uses stimulated Raman spectroscopy rather than the traditional approach of fluorescence-activated cell sorting. The new ...
Cell & Microbiology
Aug 28, 2023
0
1
When cancer spreads to the brain, treatment options fall off. Most of the drugs designed to target metastases do not cross the blood-brain barrier or are ineffective at treating brain metastases.
Bio & Medicine
Mar 31, 2023
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61
The largest genome of any insect, seven times the size of the human genome, was recently discovered in a grasshopper. In a study published in PLOS ONE, researchers from the German Leibniz Institute for the Analysis of Biodiversity ...
Plants & Animals
Mar 16, 2023
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1014
In a series of three papers on extracellular vesicles (EVs)—particles that cells use to communicate—Skoltech researchers and their colleagues have presented two methods for extracting EVs from blood samples for diagnosing ...
Cell & Microbiology
Jan 19, 2023
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8
Natural products (NPs) are low-molecular-weight compounds derived from secondary metabolic pathways, which are regulated by hierarchical regulatory networks from cluster-specific regulators to global transcriptional complexes.
Cell & Microbiology
Nov 17, 2022
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3
Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development. Fluorescent ...
Biochemistry
Sep 8, 2022
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89
A team of researchers led by Anca Dorhoi at the Friedrich-Loeffler-Institut (FLI) and Emmanuel Saliba at the Helmholtz Institute for RNA-based Infection Research (HIRI), has elucidated age-dependent variations in cellular ...
Plants & Animals
Sep 6, 2022
0
97
A recent study published in Nature Biotechnology revealed the development of high-fidelity Cas13 variants with markedly reduced collateral effects by mutagenesis and demonstrated the feasibility of hfCas13 for efficient on-target ...
Biotechnology
Aug 12, 2022
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11
Measuring the numbers and properties of cells moving in a stream—a process called flow cytometry—is critically important to diagnostic medicine, pharmaceutical research and biomedical science. Now researchers at the National ...
Cell & Microbiology
Jul 21, 2022
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27
A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery. Led by Jun Wang, Associate Professor of Biomedical Engineering ...
Biotechnology
Jun 29, 2022
0
32
