Amyloids, abnormal fibrillar aggregates of proteins, are associated with various disorders such as Alzheimer's disease. Therefore, an in-depth understanding of the mechanisms of amyloid formation is critical for developing ...
Space Exploration
Jun 16, 2020
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While amyloid plaques have long been closely associated with mechanisms driving Alzheimer's disease, visualizing how amyloid proteins assemble continues to prove difficult. The nanometer-sized amyloid fibrils are only a fraction ...
Optics & Photonics
Mar 26, 2019
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5
Researchers in the Department of Physics at King's College London have discovered that collagen fibrils can withstand a significantly higher amount of strain than previously thought, broadening our understanding of tissue ...
Biochemistry
Mar 10, 2020
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5
University at Buffalo researchers have identified for the first time an enzyme in the foxglove plant that is responsible for the production of compounds needed to make the heart failure drug digoxin.
Plants & Animals
Jul 17, 2023
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12
Amyloidosis is a multifaceted disease group caused by deposits of the misfolded "amyloid" protein in various tissues. Amyloid protein is very unique compared to other native proteins in that it has a cross-β-sheet structure, ...
Veterinary medicine
Oct 7, 2021
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4
Amyloids are protein aggregates that can form in the body, sometimes leading to diseases such as Alzheimer's. These fibrils can adopt multiple shapes, known as "polymorphs," which complicate our understanding of their role ...
Molecular & Computational biology
Jul 16, 2024
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