New techniques to assess the fate of stem cells in vivo

Stem cells ensure the development of tissues, their daily maintenance and their repair following injuries. One of the key questions in the field of stem cell biology is to define the different cell lineages in which stem ...

How packing away DNA stabilizes cell fate decisions

Susan Gasser and her group at the FMI have identified in C. elegans a much sought-for anchor protein, a previously uncharacterized chromodomain protein called CEC-4 that directly sequesters inactive chromatin at the nuclear ...

Study sheds light on stem cells

A Johns Hopkins University biologist has led a research team reporting progress in understanding the mysterious shape-shifting ways of stem cells, which have vast potential for medical research and disease treatment.

How a single molecule turns one immune cell into another

All it takes is one molecule to reprogram an antibody-producing B cell into a scavenging macrophage. This transformation is possible, new evidence shows, because the molecule (C/EBPa, a transcription factor) "short-circuits" ...

In directing stem cells, study shows context matters

Figuring out how blank slate stem cells decide which kind of cell they want to be when they grow up—a muscle cell, a bone cell, a neuron—has been no small task for science.

Scientists find trigger to decode the genome

Scientists from The University of Manchester have identified an important trigger that dictates how cells change their identity and gain specialised functions.

page 5 from 8