A deep learning-powered computational framework, 'DeepEC,' will allow the high-quality and high-throughput prediction of enzyme commission numbers, which is essential for the accurate understanding of enzyme functions.
Machine learning & AI
Jul 9, 2019
0
0
For decades, scientists and doctors have known that bacteria in soil were capable of manufacturing streptozotocin, an antibiotic compound that is also an important treatment for certain types of pancreatic cancer.
Biochemistry
Feb 7, 2019
0
148
A research team from Ruhr-Universität Bochum (RUB) and from South Africa has analysed two enzymes with identical substrate binding pockets that nevertheless convert different substrates. In the process, it emerged that changes ...
Biochemistry
Nov 7, 2018
0
6
Nicotinamide adenine dinucleotide (NAD+) is a major player in nutrition today. Studies have shown that NAD+ concentrations decrease during aging and that recovering the body's levels of NAD+ can prolong both health span and ...
Biochemistry
Oct 24, 2018
0
73
Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide.
Biochemistry
Jan 18, 2018
0
9
In a large multidisciplinary project, researchers at Karolinska Institutet have explored different properties of an enzyme family called NUDIX hydrolases. The study, published in Nature Communications, reveals novel insights ...
Biochemistry
Nov 17, 2017
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2
The catalytic activity of an enzyme called Set1A—a protein that is essential to the viability of embryonic stem cells (ESCs)—is not required for ESC self-renewal, according to a Northwestern Medicine study published in ...
Biotechnology
Oct 2, 2017
0
3
Enzymes, the micro machines in our cells, can evolve to perform new tasks when confronted with novel situations. But what if you want an enzyme to do an entirely different job—one that it would never have to do in a cell? ...
Biochemistry
Apr 22, 2015
0
32
Highlighting an important but unexplored area of evolution, scientists at The Scripps Research Institute (TSRI) have found evidence that, over hundreds of millions of years, an essential protein has evolved chiefly by changing ...
Cell & Microbiology
Sep 29, 2013
0
0
Chemists from Nijmegen, The Netherlands, have developed a catalyst that binds to DNA, slides over it and splits the molecule in particular places. The researchers were able to do this by synthetically modifying a natural ...
Materials Science
Sep 24, 2013
0
0
