Researchers have discovered a novel mechanism in Salmonella that affects its virulence and its susceptibility to antibiotics by changing its production of proteins in a previously unheard of manner. This allows Salmonella ...
Cell & Microbiology
Jul 29, 2010
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Researchers from NYU Langone Medical Center have discovered and characterized a general mechanism that controls transcription elongation in bacteria. The mechanism, described in the April 23 issue of Science, relies on physical ...
Biotechnology
Apr 22, 2010
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Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.
Molecular & Computational biology
Sep 6, 2021
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99
Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in the process that ...
Cell & Microbiology
Dec 22, 2011
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In horticultural production, growers often depend on systems that use artificial light to produce high-quality transplants. Although the systems are efficient, fluorescent lamps can produce plants with shorter shoots than ...
Plants & Animals
Jun 22, 2011
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In all living cells, DNA makes RNA and RNA makes proteins. The molecular factory that translates the information from RNA to proteins is called the "ribosome" (shown in the accompanying movie). It is a large and sophisticated ...
Cell & Microbiology
Aug 8, 2014
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A genetically encoded "live-cell" probe designed by researchers from Tokyo Tech has been able to identify phosphorylated Ser2 in the enzyme RNA polymerase II, subsequently identifying sites of the elongation phase of active ...
Cell & Microbiology
Dec 2, 2021
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81
Life depends on the precise functioning of several proteins synthesized in cells by ribosomes. This diverse set of proteins, known as a proteome, is maintained by the robust translation elongation of amino acid sequences ...
Molecular & Computational biology
Jan 5, 2023
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52
The ribosome is the protein-making "factory" within cells responsible for knitting together amino acids into polypeptide chains that form proteins.
Cell & Microbiology
Jan 22, 2015
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13
Multidrug-resistant bacteria remain a major concern for hospitals and nursing homes worldwide. Propagation of bacterial resistance is alarming and makes the search for new antimicrobials increasingly urgent. Scientists at ...
Cell & Microbiology
Dec 17, 2012
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