To infect its host, the respiratory pathogen Pseudomonas aeruginosa takes an ordinary protein usually involved in making other proteins and adds three small molecules to turn it into a key for gaining access to human cells. ...
Cell & Microbiology
May 7, 2013
0
0
Just like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!"- signal to read their part of the genomic symphony. ...
Cell & Microbiology
Jul 14, 2011
0
0
Humans need eight essential trace elements for good health, and one of them is selenium - a powerful antioxidant that is important for thyroid and brain function as well as metabolism.
Cell & Microbiology
Oct 6, 2016
0
6
At crucial points in the metabolism of all organisms, a protein with the unwieldy name of Translation Elongation Factor P (EF-P, for short) takes center stage. What it actually does during protein synthesis has only now been ...
Cell & Microbiology
Dec 14, 2012
0
0
Certain proteins are known to require Translation Factor EF-P for their synthesis, and a new study enlarges the size of the set. As some of its members are involved in bacterial pathogenicity, the results are also of therapeutic ...
Cell & Microbiology
Sep 10, 2013
0
0
Researchers have discovered a novel mechanism in Salmonella that affects its virulence and its susceptibility to antibiotics by changing its production of proteins in a previously unheard of manner. This allows Salmonella ...
Cell & Microbiology
Jul 29, 2010
0
0
In all living cells, DNA makes RNA and RNA makes proteins. The molecular factory that translates the information from RNA to proteins is called the "ribosome" (shown in the accompanying movie). It is a large and sophisticated ...
Cell & Microbiology
Aug 8, 2014
0
0
The ribosome is the protein-making "factory" within cells responsible for knitting together amino acids into polypeptide chains that form proteins.
Cell & Microbiology
Jan 22, 2015
0
13
Multidrug-resistant bacteria remain a major concern for hospitals and nursing homes worldwide. Propagation of bacterial resistance is alarming and makes the search for new antimicrobials increasingly urgent. Scientists at ...
Cell & Microbiology
Dec 17, 2012
0
0
Northwestern Medicine investigators have discovered novel mechanisms underlying a specific transcription factor essential for elongation control, the process of synthesizing RNA from DNA, according to findings published in ...
Cell & Microbiology
Aug 11, 2022
0
13
