A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
Cell & Microbiology
Oct 31, 2023
0
1
Lead optimization in drug discovery is a challenging process that heavily relies on hypotheses and the experience of medicinal chemists. This often leads to uncertain outcomes and inefficiency. Furthermore, the process is ...
Biochemistry
Oct 25, 2023
0
43
Scientists at Tufts University School of Medicine have developed a genome-scale metabolic model or "subway map" of key metabolic activities of the bacterium that causes Lyme disease. Using this map, they have successfully ...
Cell & Microbiology
Oct 19, 2023
0
8
G protein-coupled receptors (GPCRs) are the largest and most diverse group of cell surface proteins in humans. These receptors, which can be seen as "traffic directors," transmit signals from the outside to the inside of ...
Cell & Microbiology
Oct 19, 2023
0
23
Cornell researchers have harnessed the power of baker's yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds, and used the new method to identify key enzymes ...
Biochemistry
Oct 18, 2023
0
231
One double-helix strand of DNA could extend six feet, but it is so tightly coiled that it packs an entire sequence of nucleotides into the tiny nucleus of a cell. If that same DNA was instead split into two strands and divided ...
Biotechnology
Oct 17, 2023
0
85
The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages ...
Biochemistry
Oct 13, 2023
0
56
Because metal-organic frameworks (MOFs)—highly porous metal complexes—are so structurally and chemically diverse, they could be used for many applications, such as drug delivery and environmental clean-up. But researchers ...
Analytical Chemistry
Oct 11, 2023
0
1
A team of researchers has found a way to speed up the creation of quantum entanglement, a mystifying property of quantum mechanics that Albert Einstein once described as "spooky action at a distance."
Quantum Physics
Oct 9, 2023
6
119
Snakebites cause around 100,000 deaths worldwide every year. Researchers at the Technical University of Munich (TUM) have investigated how the toxin emerged between 50 and 120 million years ago through the modification of ...
Evolution
Oct 9, 2023
0
131
