The rise, fall and resurgence of gene therapy

Twenty years ago, scientists and investors were giddy over the promise of gene therapy to cure a host of deadly diseases. But the tragic death of a young man from an experimental treatment in 1999 nearly ended a scientist's ...

How does an intestinal microbe become a pathogen?

The bacterium Escherichia coli is found in the human intestine, and elsewhere. There it is harmless, but in certain conditions it can become a pathogen. It can cause bladder infections or even sepsis. A team of researchers ...

New method may lead to better in vivo drug delivery

At some point, every person is likely to experience an inflammatory condition. There are many causes of inflammation, and just as many treatments. Some types of inflammation disappear by themselves, while others require medical ...

Cells protect themselves against stress by keeping together

Cell-to-cell contacts are necessary for the survival of human cells under protein-damaging conditions and stress. This was one of the conclusions made by a research team working under the leadership of Lea Sistonen, Professor ...

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