Southwest Research Institute (SwRI) has developed a unique software program that enables prescreening of the three-dimensional structure of proteins and enzymes for pharmaceutical and biochemical research prior to drug synthesis. ...
Biochemistry
Jan 11, 2013
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Viruses can be elusive quarry. RNA viruses are particularly adept at defeating antiviral drugs because they are so inaccurate in making copies of themselves. With at least one error in every genome they copy, viral genomes ...
Cell & Microbiology
Nov 20, 2012
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Despite its small size, the fluorine atom has had a vast impact on the pharmaceutical industry. More often than not, introducing fluorine to a drug molecule improves the drug's biological activity, earning it a reputation ...
Materials Science
Oct 3, 2012
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In 2010 malaria caused an estimated 665,000 deaths, mostly among African children. Now, chemists at Indiana University have developed a new synthesis for the world's most useful antimalarial drug, artemisinin, giving hope ...
Biochemistry
Sep 13, 2012
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Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information ...
Biochemistry
Aug 21, 2012
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A trawl of the genome of the deadly bacterium Bacillus anthracis has revealed a clutch of targets for new drugs to combat an epidemic of anthrax or a biological weapons attack. The targets are all proteins that are found ...
Cell & Microbiology
Aug 20, 2012
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University of Saskatchewan researchers have discovered the chemical pathway that Cannabis sativa uses to create bioactive compounds called cannabinoids, paving the way for the development of marijuana varieties to produce ...
Biochemistry
Jul 16, 2012
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Organic chemists seek synthesis reactions that produce high yields of very pure products. European researchers have developed novel synthetic reactions for a class of compounds particularly relevant to potential drug therapies.
Biochemistry
Jul 6, 2012
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The search for new drug candidates for cancer treatment is laborious and time-consuming. Only a fraction of the promising chemical compounds identified completes the transition to the market. Herbert Waldmann and his team ...
Biochemistry
Feb 28, 2012
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(PhysOrg.com) -- New active substances can be produced quickly and efficiently with the help of reaction cascades. Once set in motion, these processes lead to the desired end product via a series of intermediate steps which ...
Biochemistry
Dec 26, 2011
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