Review: PROTACs targeting epigenetic proteins

The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...

Trifunctional molecule decodes cellular communication

(Phys.org)—How does one define the factors on the surface of human cells to which a molecule of interest binds? This question is typically hard to answer. Researchers of ETH Zurich have developed a new technology that enables ...

New brain sensor offers answers about Alzheimer's

Scientists at the University of Virginia School of Medicine have developed a tool to monitor communications within the brain in a way never before possible, and it has already offered an explanation for why Alzheimer's drugs ...

ONR technology to aid in war on drugs

A multi-agency task force charged with eliminating illegal drug trafficking is installing a new software technology developed by the Office of Naval Research (ONR), the command announced July 21.

UK researcher sentenced to three months' jail for faking data

A British scientist convicted of scientific fraud last month for falsifying research data has been sentenced to three months jail. Steven Eaton is the first person to serve time under the UK's Good Laboratory Practice Regulations, ...

Researchers identify mechanism that maintains stem cells readiness

An immune-system receptor plays an unexpected but crucially important role in keeping stem cells from differentiating and in helping blood cancer cells grow, researchers at UT Southwestern Medical Center report today in the ...

Team develops new drug discovery platform

A highly versatile family of receptors found on the surface of our cells plays a massive role in the multibillion-dollar field of drug discovery. Called G protein-coupled receptors, or GPCRs, they also facilitate a staggering ...

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