Researchers at the University of Helsinki, together with researchers from the United States, have discovered a small molecule that inhibits the formation in cells of cytokine proteins that promote inflammation. The mechanism ...
Biochemistry
Jun 7, 2023
0
40
Chirality of molecules is a crucial consideration in drug development as the enantiomeric purity of a compound can significantly impact its pharmacological properties. Chiral molecules possess mirror-image enantiomers that ...
Analytical Chemistry
Jun 6, 2023
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3
A new "molecular editing" technique from Scripps Research enables chemists to add new elements to organic molecules at locations that were previously out of reach.
Analytical Chemistry
May 31, 2023
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14
Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity. They captured six structures ...
Cell & Microbiology
May 23, 2023
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83
In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency. Solubilizing agents such ...
Biochemistry
May 15, 2023
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48
Chemotherapy that does not harm the body, but effectively fights cancer cells: that is the goal of chemist Sylvestre Bonnet and his team. During his Ph.D. research, chemist Xuequan Zhou brought that goal a little closer. ...
Bio & Medicine
May 12, 2023
0
113
Research in the International Journal of Computational Biology and Drug Design, has looked at the potential of various bioflavonoids as inhibitors of the SARS-CoV-2 virus, which causes COVID-19. The compounds—narirutin, ...
Biochemistry
May 4, 2023
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6
A new type of drug could provide a way to treat multidrug-resistant bacteria, according to a study published in Nature Communications. Instead of targeting the bacteria directly, the drug blocks key toxins involved in the ...
Cell & Microbiology
Apr 18, 2023
1
67
There is a need for new drugs. For example, many of the antibiotics that we have been using for a long time are becoming less effective. Chemists and pharmaceutical scientists are frantically searching for new active substances, ...
Biochemistry
Apr 13, 2023
0
38
If you know the atoms that compose a particular molecule or solid material, the interactions between those atoms can be determined computationally, by solving quantum mechanical equations—at least, if the molecule is small ...
Quantum Physics
Apr 7, 2023
0
125
