Seeing small-molecule interactions inside cells

Like people in a large company, proteins in cells constantly interact with each other to perform various jobs. To develop new disease therapies, researchers are trying to control these interactions with small-molecule drugs ...

Rules governing RNA's anatomy revealed

(PhysOrg.com) -- University of Michigan researchers have discovered the rules that dictate the three-dimensional shapes of RNA molecules, rules that are based not on complex chemical interactions but simply on geometry.

An end to animal testing for drug discovery?

As some countries and companies roll out new rules to limit animal testing in pharmaceutical products designed for people, scientists are stepping in with a new way to test therapeutic drug candidates and determine drug safety ...

Melting reveals drug targets in a living organism

Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases. An international team led by researchers at the European Molecular Biology Laboratory ...

Revealing physical mechanisms behind the movement of microswimmers

Bacteria and other unicellular organisms developed sophisticated ways to actively navigate their way, despite being comparably simple structures. To reveal these mechanisms, researchers from the Max Planck Institute for Dynamics ...

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