Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create ...
Biochemistry
Jun 7, 2022
0
72
Chemists at Scripps Research have unveiled a method for turning cheap and widely available chemicals known as dicarboxylic acids into potentially very valuable molecules called lactones.
Materials Science
May 27, 2022
0
125
FMI researchers have identified a synthetic protein that dampens the activity of a cellular pathway involved in viral infection. The findings could help to develop drugs that combat viruses such as influenza A and Zika.
Cell & Microbiology
May 11, 2022
0
117
Scientists rely increasingly on models trained with machine learning to provide solutions to complex problems. But how do we know the solutions are trustworthy when the complex algorithms the models use are not easily interrogated ...
Analytical Chemistry
May 2, 2022
0
95
Modern drug discovery is an expensive and complicated process. Hundreds of scientists and at least a decade are often required to produce a single medicine. One of the most critical steps in this process is the first one—identifying ...
Biochemistry
Apr 21, 2022
0
10
Researchers at Stockholm University have applied advanced electron microscopy techniques to finally unveil the structure of the widely used and century-old active pharmaceutical ingredient bismuth subsalicylate. The discovery ...
Analytical Chemistry
Apr 13, 2022
0
31
Scientists at Scripps Research and the National Institute of Dental and Craniofacial Research have discovered a special type of cell that resides in salivary glands and is likely crucial for oral health.
Cell & Microbiology
Apr 12, 2022
0
54
Demand for new kinds of antibiotics is surging, as drug-resistant and emerging infections are becoming an increasingly serious global health threat. Researchers are racing to reexamine certain microbes that serve as one of ...
Cell & Microbiology
Apr 11, 2022
0
139
Scientists have developed a new technique to accelerate the discovery of cancer-fighting drugs. The technique identifies molecules that can shut down dangerous proteins before they wreak disease-triggering havoc, by blocking ...
Biochemistry
Apr 7, 2022
0
85
In a new study at University of California, Irvine, researchers have revealed the impact of native lipids on rhodopsin signaling and regeneration, which may usher in a new paradigm for discovery of drugs that target G protein-coupled ...
Cell & Microbiology
Apr 7, 2022
0
48
