Scripps Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'miniecosystems' to quickly see if a molecule can function as a potential therapeutic.
Analytical Chemistry
Jun 18, 2018
0
101
Inspired by natural products, scientists on the Florida campus of the Scripps Research Institute have created a new class of small molecules with the potential to serve as a rich foundation for drug discovery.
Biochemistry
Nov 20, 2011
1
0
(PhysOrg.com) -- Flasks, beakers and hot plates may soon be a thing of the past in chemistry labs. Instead of handling a few experiments on a bench top, scientists may simply pop a microchip into a computer and instantly ...
Analytical Chemistry
Aug 3, 2009
3
0
Microscopy has been making leaps and bounds in recent years. Science that was inconceivable a few years ago has become a matter of programming state-of-the-art microscopes to process reams of data. Dr. Gabriel Frank quickly ...
Molecular & Computational biology
Aug 5, 2024
0
17
Developing a new drug can take years of research and cost millions of dollars. Still, more than 90% of drug candidates fail in clinical trials, with even more that never make it to the clinical stage. Many drugs fail because ...
Biochemistry
Jul 18, 2024
0
16
Nightshade plants produce a diverse array of compounds with therapeutic potential. Researchers at CeMM have now identified an artificial variant inspired by the Withanolides group that acts highly specifically against leukemia ...
Cell & Microbiology
Jun 21, 2024
0
18
A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
Cell & Microbiology
Oct 31, 2023
0
1
When a human consumes a pharmaceutical drug, enzymes in the liver break down the substance into metabolites that are water soluble, so the body can more easily excrete them. In some cases, the resulting metabolites may have ...
Biochemistry
Jul 13, 2023
0
9
A new publication in the May issue of Nature Aging by researchers from Integrated Biosciences, a biotechnology company combining synthetic biology and machine learning to target aging, demonstrates the power of artificial ...
Biotechnology
May 8, 2023
0
6801
A research team co-led by chemists from City University of Hong Kong (CityU) recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity ...
Biochemistry
Apr 6, 2023
0
18
