Scripps Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'miniecosystems' to quickly see if a molecule can function as a potential therapeutic.
Analytical Chemistry
Jun 18, 2018
0
101
Searching for new drugs is like fishing in the dark: the prospect of catching something is very uncertain, and it requires patience, skill and – of course – money. ETH researchers led by Dario Neri have developed a new ...
Biochemistry
Mar 28, 2018
0
12
McMaster University engineers have devised a way to make testing for new drugs more efficient and affordable, and reduce the time for helpful medications to reach the public.
Biochemistry
Feb 9, 2018
0
7
A new (and freely available) original research article by Barbara M. Zietek et al., now available ahead-of-print at SLAS Discovery Online, presents a fast, robust and accurate methodology for correlating compound identity ...
Biochemistry
Dec 21, 2017
0
15
Scientists at DESY have developed a new method that enables automated and fast screening of promising drug candidates. This novel technique, called mix-and-diffuse serial synchrotron crystallography, can image the interaction ...
Biochemistry
Dec 8, 2017
0
3
A widely used screening tool deployed in the early phases of drug discovery to weed out undesirable compounds is wrong so often it can't be trusted on its own, according to scientists at the University of North Carolina at ...
Biochemistry
Jul 11, 2017
0
2
Drug discovery may bring to mind images of white lab coats and pipettes, but when Henry Lin, PhD, recently set out to find a better opioid with fewer side effects, his first step was to fire up the computers.
Biochemistry
Apr 6, 2017
0
9
In a pair of firsts, researchers at Case Western Reserve University and Massachusetts Institute of Technology have shown that the drug candidate phenanthriplatin can be more effective than an approved drug in vivo, and that ...
Bio & Medicine
Jun 8, 2016
0
1935
In an important new study with implications for the treatment of dozens of incurable diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time created a drug candidate that ...
Biochemistry
Jun 1, 2016
0
837
Scientists using a technology called cryo-EM (cryo-electron microscopy) have broken through a technological barrier in visualizing proteins with an approach that may have an impact on drug discovery and development. They ...
Biochemistry
May 26, 2016
0
191
