Crystallized alternative DNA structure sheds light on insulin and diabetes
The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team.
The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team.
Molecular & Computational biology
Sep 6, 2024
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147
A collaboration between researchers at the Laboratory of Medical Sciences (LMS) in London and the Laboratory of Molecular Biology (LMB) in Cambridge, has solved a decades-old mystery which could pave the way to better cancer ...
Molecular & Computational biology
Jul 31, 2024
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402
Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in every cell in the body ...
Cell & Microbiology
Apr 11, 2024
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146
Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling single-strand end into intact ...
Molecular & Computational biology
Jan 22, 2024
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36
A team led by Professor Michal Hocek at IOCB Prague has explored the limits of the structure and function of DNA and successfully pushed forward known boundaries. Their latest research has just been published in Nucleic Acids ...
Molecular & Computational biology
Nov 9, 2023
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183
The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location of imperfect complementary ...
Biochemistry
Oct 17, 2023
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356
A human cell harbors roughly 2 meters of DNA, encompassing the essential genetic information of an individual. If one were to unwind and stretch out all the DNA contained within a single person, it would span a staggering ...
Biotechnology
Jun 16, 2023
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1718
Researchers at the University at Albany's RNA Institute have demonstrated a new approach to DNA nanostructure assembly that does not require magnesium. The method improves the biostability of the structures, making them more ...
Cell & Microbiology
Jun 6, 2023
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225
A previously overlooked letter and a news article that was never published, both written in 1953, add to other lines of evidence showing Rosalind Franklin was an equal contributor—not a victim—in the discovery of DNA's ...
Molecular & Computational biology
Apr 25, 2023
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120
DNA replication is the process whereby cells make an exact copy of their DNA before cell division. A key part of the intricate DNA replication machinery is a molecular motor called CMG, which has the vital task of separating ...
Biotechnology
Apr 20, 2023
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242