'Undruggable' Parkinson's molecule spills its secrets

UC San Francisco researchers have for the first time developed a strategy for targeting a key molecule implicated in Parkinson's disease, opening up a potential new treatment strategy for the currently incurable movement ...

Cell membranes: Synthetics save time and cut costs

Screening for critical drug targets known as G-protein-coupled receptors (GPCRs) is now possible without the need to extract these proteins from their native cells. Extraction requires the use of stabilizing lipids, which ...

New nanosensor gives unprecedented look at dopamine release

Astronomers build new telescopes and peer at the night sky to see what they might find. Janelia Group Leader Abraham Beyene takes a similar approach when looking at the cells that make up the human brain.

A microscopic worm may shed light on how we perceive gravity

While humans rely on gravity for balance and orientation, the mechanisms by which we actually sense this fundamental force are largely unknown. Odder still, the model organism C. elegans, a microscopic worm, can also sense ...

The secrets of polydopamine coatings revealed

Dopamine is best known as a neurotransmitter. What is rather unknown, however, is that the underwater glue used by mussels contains large amounts of L-Dopa molecules, an analog of dopamine.

What makes birds so smart?

Researchers at Ruhr University Bochum explain how it is possible for the small brains of pigeons, parrots and corvids to perform equally well as those of mammals, despite their significant differences.

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