DNA structure impacts rate and accuracy of DNA synthesis

The speed and error rate of DNA synthesis is influenced by the three-dimensional structure of the DNA. Using "third-generation" genome-wide DNA sequencing data, a team of researchers from Penn State and the Czech Academy ...

Revolutionary process could signal new era for gene synthesis

A team of scientists led by the University of Southampton has demonstrated a groundbreaking new method of gene synthesis - a vital research tool with real-world applications in everything from growing transplantable organs ...

Structure of key DNA replication protein solved

A research team led by scientists at the Icahn School of Medicine at Mount Sinai (ISMMS) has solved the three-dimensional structure of a key protein that helps damaged cellular DNA repair itself. Investigators say that knowing ...

Key to regulating cell's powerhouse discovered

Aging, neurodegenerative disorders and metabolic disease are all linked to mitochondria, structures within our cells that generate chemical energy and maintain their own DNA. In a fundamental discovery with far-reaching implications, ...

New chromosome origin element identified

Newcastle University scientists have discovered a new essential sequence within bacterial genomes required for DNA replication - the second ever to be discovered and the first for 30 years.

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