Related topics: genome

A nanoprobe with a barcode: Sensors detect active proteases

Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like ...

Molecular VELCRO for chromosome stability

(Phys.org) —A team of scientists at the Friedrich Miescher Institute for Biomedical Research and the University of Geneva has functionally dissected the molecular processes that ensure the stability of chromosomes. They ...

DNA's double stranded stretch

(Phys.org)—Theoretical physicists like to play with very unconventional toys. Manoel Manghi from Toulouse University in France and his colleagues have adopted a seemingly playful approach to examining what happens to a ...

How knots can swap positions on a DNA strand

Physicists of Johannes Gutenberg University Mainz (JGU) and the Graduate School of Excellence "Materials Science in Mainz" (MAINZ) have been able with the aid of computer simulations to confirm and explain a mechanism by ...

How E. coli defends itself against antibiotics

Imagine that you have a very sore throat. You're sick, your throat hurts, and a visit to the doctor confirms that the pain is due to a bacterial infection. You get a prescription for antibiotics, which quickly sorts out your ...

Why wasn't the human genome shredded long ago?

In the January 7th edition of Communications Biology, researchers at InsideOutBio argue that an unusual form of DNA with a reverse twist may have helped thwart the invasion of the human genome by junk DNA. This mechanism ...

A record-long polymer DNA negative

A fragment of a single strand of DNA, built of the nucleobases cytosine and guanine, can be imprinted in a polymer—this has been shown by chemists from Warsaw, Denton and Milan. The resulting artificial negative, with a ...

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