When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.
Cell & Microbiology
Mar 21, 2022
0
35
Human cytomegalovirus (HCMV) replicates its DNA genome in specialized replication compartments, whose exact formation was thus far unclear. A research team from the Leibniz Institute for Experimental Virology (HPI) and the ...
Cell & Microbiology
Mar 9, 2022
0
31
A new study from scientists at the UNC School of Medicine has illuminated an important process that occurs during cell division and is a likely source of DNA damage under some circumstances, including cancer.
Cell & Microbiology
Jan 26, 2022
0
69
Beneath the SARS-CoV-2 membrane and its spikes lurks a squiggle of genetic material, or RNA, enveloped by a protein that acts like bubble wrap to protect the genetic material. This protein also acts as a "hotbed" for multiple ...
Molecular & Computational biology
Jan 18, 2022
0
678
Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.
Molecular & Computational biology
Nov 22, 2021
0
848
Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using ...
Biotechnology
Nov 19, 2021
1
476
Genes aren't only inherited through birth. Bacteria have the ability to pass genes to each other, or pick them up from their environment, through a process called horizonal gene transfer, which is a major culprit in the spread ...
Molecular & Computational biology
Oct 22, 2021
0
255
Researchers at the Andalusian Molecular Biology and Regenerative Medicine Centre (CABIMER) and the University of Seville have taken another step in the study of genetic instability, as manifested in cancer cells. This has ...
Molecular & Computational biology
Oct 5, 2021
0
41
Cornell researchers have identified a new way to measure DNA torsional stiffness—how much resistance the helix offers when twisted—information that can potentially shed light on how cells work.
General Physics
Aug 11, 2021
0
891
Researchers have analyzed the three-dimensional structure of a protein that suppresses the development of colorectal polyposis, MUTYH, at the atomic level and clarified the repair mechanism for DNA mispairings by MUTYH. Since ...
Biotechnology
Aug 2, 2021
0
82
