Scientists determine structure of a DNA damage 'first responder'
DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.
DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.
Molecular & Computational biology
Mar 21, 2022
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73
Using the Summit supercomputer at the U.S. Department of Energy's (DOE's) Oak Ridge National Laboratory (ORNL), a Georgia State University (GSU) research team has revealed the structural mechanism of the Cockayne Syndrome ...
Cell & Microbiology
Feb 10, 2022
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32
Since the discovery of CRISPR/Cas9, also known as molecular scissors, scientists around the world have been working to improve the revolutionary technique for altering DNA that earned Emmanuelle Charpentier and Jennifer Doudna ...
Molecular & Computational biology
Feb 9, 2022
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72
A simple, marine-dwelling creature known as Trichoplax adhaerens has some remarkable properties. The organism can tolerate unusually high doses of radiation that would kill most other forms of life. T. adhaerens has another ...
Cell & Microbiology
Jan 3, 2022
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525
Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects ...
Cell & Microbiology
Dec 28, 2021
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254
An organism's genome could be compared to a complex system of instructions that allows it not only to develop, but also to carry out all the activities essential to its survival. To do this, this genome needs to be expressed ...
Molecular & Computational biology
Dec 3, 2021
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158
Research carried out at the Institute of Molecular Biology and Biotechnology (IMBB) of FORTH, provides evidence that persistent DNA damage triggers an exosome-based, metabolic reprogramming that leads to chronic inflammation ...
Cell & Microbiology
Nov 26, 2021
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154
Rockfish is on the menu around the Pacific Rim, for the most part with little regard for the fish's origin or which of the 137 species is on the plate—it's typically identified simply as rockfish or, incorrectly, as rock ...
Biotechnology
Nov 11, 2021
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224
How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university ...
Molecular & Computational biology
Sep 1, 2021
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69
Studying DNA repair is key to future space exploration, which could expose humans to risk of DNA damage caused by radiation. Conditions in space also could affect the way the body repairs such damage, potentially compounding ...
Space Exploration
Aug 18, 2021
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612