Scientists extend mechanism for cracking biochemical code

Since the time of ancient Egypt, humans have been making and breaking secret codes to retain and gain critical information. Human life itself is based upon a genetic code of DNA or RNA sequences which cells read and translate ...

How chemical modifications on DNA keep genes silent

Several diseases, including certain types of cancer and some neurodevelopmental conditions, have aberrant patterns of DNA methylation, a chemical modification that regulates gene expression in ways that keep genes in the ...

Dual systems key to keeping chromosomes intact

USC scientists have discovered how two different structural apparatuses collaborate to protect repetitive DNA when it is at its most vulnerable – while it is being unzipped for replication.

Recipe for making a fruitfly

Researchers have used mass spectroscopy to determine the absolute copy numbers of nuclear proteins and histone modifications in the Drosophila embryo. The results provide new insights into the mechanisms of animal development.

New technique efficiently offers insight into gene regulation

DNA is the most important carrier of genetic information. Each cell contains approximately two meters of DNA. To ensure that all this genetic material fits into the small cell nucleus, it must be tightly packed. The DNA is, ...

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