A new imaging technique has allowed researchers at North Carolina State University, the University of North Carolina at Chapel Hill, and the University of Pittsburgh to see how DNA loops around a protein that aids in the ...
Cell & Microbiology
Feb 11, 2016
0
1233
Protein factors are responsible for organizing chromosomes inside the nucleus in three dimensions (3D), forming a shape like a gift bow, with proteins aggregating as the central 'knot' holding the ribbon-like loops of DNA ...
Cell & Microbiology
Dec 10, 2015
0
9
A research team based in Houston's Texas Medical Center has found that the proteins that turn genes on by forming loops in human chromosomes work like the sliding plastic adjusters on a grade-schooler's backpack. This discovery ...
Biotechnology
Oct 19, 2015
2
1040
In spore-forming bacteria, chromosomal locations of genes can couple the DNA replication cycle to critical, once-in-a-lifetime decisions about whether to reproduce or form spores. The new finding by Rice University bioengineers ...
Cell & Microbiology
Jul 9, 2015
8
784
Contrary to what was thought, sequences of DNA called enhancers – which control a gene's output – find their targets long before they are activated during embryonic development, scientists at the European Molecular Biology ...
Cell & Microbiology
Jul 3, 2014
0
0
(Phys.org)—In certain toy racecar tracks, sneaky players can flip a switch, trapping their opponents' vehicles in a loop of track. Cells employ a less subtle approach: they change the track's layout. In a study published ...
Cell & Microbiology
Sep 28, 2012
0
0
In exploring how proteins interact with crucial DNA sequences to regulate gene activity, researchers have shed light on key biological events that may eventually be manipulated to provide new disease treatments.
Cell & Microbiology
Jun 7, 2012
0
0
Researchers report that a single-stranded DNA-binding protein (SSB), once thought to be a static player among the many molecules that interact with DNA, actually moves back and forth along single-stranded DNA, gradually allowing ...
Biochemistry
Oct 21, 2009
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1
The tools of biochemistry have finally caught up with lactose repressor protein. Biologists from Rice University in Houston and the University of Florence in Italy this week published new results about "lac repressor," which ...
Biochemistry
Sep 22, 2009
0
0
(PhysOrg.com) -- Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many ...
General Physics
Mar 16, 2009
0
0
