An international team of scientists led by Jef Boeke, PhD, director of NYU Langone Medical Center's Institute for Systems Genetics, has synthesized the first functional chromosome in yeast, an important step in the emerging ...
Cell & Microbiology
Mar 27, 2014
25
0
Remarkably, living cells are able to package a jumble of DNA over two meters in length into tidy, tiny chromosomes while preparing for cell division. However, scientists have been puzzled for decades about how the process ...
Cell & Microbiology
Feb 22, 2018
1
242
(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would be crammed into ...
Cell & Microbiology
Jan 17, 2012
5
0
Improved pest resistance and drought tolerance are among potential benefits of an international effort in which Agricultural Research Service (ARS) scientists and their collaborators have produced the clearest picture yet ...
Biotechnology
May 1, 2019
0
140
Data, data everywhere and now as ever researchers need the best tools to make the data useful. In medicine, searching through genomic data can take some time. A startup called One Codex hopes to make difference with their ...
Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED. TALEDs are base editors ...
Biotechnology
Apr 25, 2022
0
44
DNA is the instruction manual for every living organism, guiding the development and functioning of all biological processes. In essence, it is a molecule with a double helix structure with each unit of a helix containing ...
Molecular & Computational biology
Sep 13, 2021
0
466
Scientists at the Institute for Research in Biomedicine (IRB Barcelona) have found an explanation for a periodicity in the sequence of the genomes of all eukaryotes, from yeast to humans. The results published in the journal ...
Molecular & Computational biology
Nov 2, 2018
8
291
A Massachusetts General Hospital (MGH) research team reports that several of the recently developed CRISPR base editors, which create targeted changes in a single DNA base, can induce widespread off-target effects in RNA, ...
Biotechnology
Apr 17, 2019
0
189
An international team of researchers has succeeded in making 13,200 edits to a single cell—and the cell survived. In their paper uploaded to the bioRxiv preprint server, the team describes the edits they made, how they ...
