This year, we celebrate 10 years of genome editing with CRISPR. The system is often referred to as molecular scissors, and this designation is quite accurate for its first applications. These short 10 years were marked by ...
Biotechnology
Jul 6, 2022
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Veterinarians at the University of California, Davis, have found that a cat's DNA alters how it responds to a life-saving medication used to treat hypertrophic cardiomyopathy, or HCM, a heart disease that affects 1 in 7 cats. ...
Veterinary medicine
Jul 6, 2021
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Noonan syndrome (NS) and Noonan syndrome with multiple lentigines (NS-ML) are rare human developmental disorders caused by mutations of the protein SHP2. Until recently, the mechanism of NS and NS-ML pathogenesis had been ...
Molecular & Computational biology
Oct 1, 2020
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Base editors, which enable production of highly efficient targeted point mutations in genomic DNA without causing double-stranded DNA breaks, hold great promise for gene therapy in human disease and trait improvement in crop ...
Biotechnology
Jul 27, 2020
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Research groups from Instituto Gulbenkian de Ciência (IGC) that study evolution, immunity and microbiology unveiled two new mechanisms in the microbiota: in older populations, the bacterium E. coli evolves in a way that ...
Evolution
Mar 12, 2020
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Laryngeal paralysis is a serious and sometimes deadly disease in some dog breeds that prevents proper opening of the larynx for breathing. In a new study published 24th October in PLOS Genetics, a team of German specialists ...
Veterinary medicine
Oct 24, 2019
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Studying the fundamental aspects of biology can sometimes lead to unexpected findings that directly relate to human disease. In one of the latest examples of scientific serendipity, researchers from the Salk Institute found ...
Cell & Microbiology
Sep 14, 2018
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Using a variation of CRISPR gene editing may be a potential strategy for mimicking the protective effects of a genetic mutation linked to lower cholesterol levels and heart disease risks, according to new mouse research from ...
Biotechnology
Feb 27, 2018
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Following genetic studies of deformed calves research conducted at the University of Copenhagen is able to uncover a hitherto unknown disease found among Holstein cattle. The breeding bull from which the mutation and thus ...
Plants & Animals
Sep 21, 2017
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An international team of researchers has found a way to diagnose disease and predict patient outcomes simply by measuring unbelievably small changes in interactions between molecules inside the body. The simple new technique ...
Bio & Medicine
Sep 12, 2017
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