Non-Mendelian, oligogenic inheritance could be an unrecognized and important element for occurrence of hereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and ...
Evolution
Jul 19, 2019
0
70
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent ...
Molecular & Computational biology
Feb 19, 2019
0
45
Alport syndrome (AS) is a hereditary kidney disease caused by a genetic mutation leading to type IV collagen (Col4) abnormalities. Unfortunately, treatment through the correction of Col4 functionality has not yet been developed. ...
Biochemistry
Mar 9, 2018
0
32
Nucleic acid sequencing methods, which determine the order of nucleotides in DNA fragments, are rapidly progressing. These processes yield large quantities of sequence data—some of which is dynamic—that helps researchers ...
Mathematics
Dec 28, 2017
0
345
Scientists have identified the genetic mutations that cause sickle cells in deer, according to new research in the journal Nature Ecology & Evolution.
Ecology
Dec 20, 2017
0
48
In a study analyzing the genomes of 210,000 people in the United States and Britain, researchers at Columbia University find that the genetic variants linked to Alzheimer's disease and heavy smoking are less frequent in people ...
Evolution
Sep 5, 2017
2
132
For breeders of cassava, a staple food for hundreds of millions in the tropics, producing improved varieties has been getting harder over time. A team at Cornell used genomic analysis of cassava varieties and wild relatives ...
Biotechnology
Apr 28, 2017
6
685
Guan-En Graham is determined to find out exactly what happened to her father. When she was a child, he developed brain cancer. Since then, she has worked to understand the intricate genetic mechanisms that trigger brain diseases ...
Biotechnology
Jan 18, 2017
0
392
Despite a billion years of evolution separating humans from the baker's yeast in their refrigerators, hundreds of genes from an ancestor that the two species have in common live on nearly unchanged in them both, say biologists ...
Biotechnology
May 21, 2015
5
58
Researchers have traced genetic changes in a bacterial pathogen over 450 years, and claim that epidemics of bacterial disease in human history may be caused by chance environmental changes rather than genetic mutations.
Cell & Microbiology
Aug 4, 2014
0
0
