A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies ...
Cell & Microbiology
Apr 13, 2023
0
45
Although the regulation of sleep—how much, when, and how sleep occurs—is mainly considered to be controlled by the brain, sleep deprivation also affects the body, and signals from the body can affect sleep. However, the ...
Cell & Microbiology
Mar 27, 2023
0
35
The p97 protein is one of your body's best garbage disposers. It floats around in your cells looking for signals that a protein is past its shelf life and needs to be trashed. Mutations in this protein have been linked to ...
Cell & Microbiology
Feb 7, 2023
0
39
Researchers have discovered a surprising anomaly in the behavior of how proteins form, upending long-held assumptions about the way cells produce these crucial molecules and potentially leading to a better understanding of ...
Biochemistry
Jan 16, 2023
0
44
University of Massachusetts Amherst research into genetic mutations that affect circadian rhythms offers new insight into the rest-wake cycle and provides a new model for investigating human disease and ultimately developing ...
Cell & Microbiology
Oct 20, 2022
0
78
For the first time, scientists will be able to test therapeutics for a group of rare neurodegenerative diseases that affect infants and young children, thanks to a new research model created by scientists at the University ...
Cell & Microbiology
Sep 26, 2022
0
68
Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...
Molecular & Computational biology
Aug 5, 2022
0
80
Thanks to advances in genomics in recent decades, researchers now know the genetic mutations responsible for many diseases. However, researchers often still do not know how the mutation leads to the disease—what it changes ...
Cell & Microbiology
Jul 11, 2022
0
500
A new single-cell RNA-sequencing protocol developed at Institute of Molecular and Clinical Ophthalmology Basel (IOB) enables the detection of a significantly higher number of genes per cell than any existing method. It is ...
Cell & Microbiology
May 30, 2022
0
118
When genes mutate, this can lead to severe diseases of the human nervous system. Researchers at Leipzig University and the University of Würzburg have now used fruit flies to demonstrate how, apart from the negative effect, ...
Other
May 10, 2022
0
399
