Whether it is a drug-resistant strain of bacteria, or cancer cells that no longer react to the drugs intended to kill them, diverse mutations make cells resistant to chemicals, and "second generation" approaches are needed. ...
Biotechnology
Mar 24, 2020
0
144
EPFL scientists have developed a computational method modeling and designing protein allostery that allows the accurate and rational engineering and even repurposing of cell receptors. The method can be a significant tool ...
Biochemistry
Dec 2, 2019
0
36
Rice University chemists want to make a point: Nitrogen atoms are for squares.
Materials Science
Aug 9, 2019
0
114
Scientists at Nanyang Technological University, Singapore (NTU Singapore) have engineered an antiviral peptide that exploits the Zika virus at its Achilles' heel—the viral membrane—hence stopping the virus from causing ...
Biochemistry
Oct 24, 2018
0
24
Drug overdoses are taking a huge toll on public health, with potent synthetic drugs posing a particular threat. Medical professionals are scrambling to meet the growing demand for emergency room treatment, but they're hampered ...
Analytical Chemistry
Mar 19, 2018
0
37
Scientists at The Scripps Research Institute (TSRI) have peered deep into the heart of a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases. The protein, ...
Biochemistry
Dec 28, 2017
0
324
Researchers at McMaster University have developed a new drug screening technique that could lead to the rapid and accurate identification of fentanyl, as well as a vast number of other drugs of abuse, which up until now have ...
Analytical Chemistry
Nov 2, 2017
0
141
Scientists have created a high-speed method to generate thousands of different, small, stable proteins from scratch that can be custom-designed to bind to specific therapeutic targets.
Biochemistry
Sep 27, 2017
0
331
EPFL scientists have created a new computer model that can help better design of allosteric drugs, which control proteins "at a distance".
General Physics
Feb 20, 2017
0
745
Scientists at The Scripps Research Institute (TSRI) have developed a vaccine that blocks the pain-numbing effects of the opioid drugs oxycodone (oxy) and hydrocodone (hydro) in animal models. The vaccine also appears to decrease ...
Biochemistry
Nov 23, 2016
4
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