Designing and repurposing cell receptors

EPFL scientists have developed a computational method modeling and designing protein allostery that allows the accurate and rational engineering and even repurposing of cell receptors. The method can be a significant tool ...

Peptide exploits Achilles' heel of Zika virus

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have engineered an antiviral peptide that exploits the Zika virus at its Achilles' heel—the viral membrane—hence stopping the virus from causing ...

Identifying 'designer' drugs taken by overdose patients

Drug overdoses are taking a huge toll on public health, with potent synthetic drugs posing a particular threat. Medical professionals are scrambling to meet the growing demand for emergency room treatment, but they're hampered ...

New structure of key protein holds clues for better drug design

Scientists at The Scripps Research Institute (TSRI) have peered deep into the heart of a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases. The protein, ...

Molecules change shape when wet

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers led by Melanie Schnell from the Max Planck Institute for the Structure and Dynamics of Matter at ...

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