Cellular RNA can template DNA repair in yeast

The ability to accurately repair DNA damaged by spontaneous errors, oxidation or mutagens is crucial to the survival of cells. This repair is normally accomplished by using an identical or homologous intact sequence of DNA, ...

Reconstructing the life history of a single cell

Researchers have developed new methods to trace the life history of individual cells back to their origins in the fertilised egg. By looking at the copy of the human genome present in healthy cells, they were able to build ...

The sonic screwdriver can turn cells tartan

It's the sort of thing you would expect Dr Who to do – join up someone's damaged nerves by using a sonic screwdriver. But the scientists at the University of Glasgow are no time-travellers and their work is based in a lab ...

How DNA damage affects Golgi—the cell's shipping department

In studying the impact of DNA damage on the Golgi, a research team from the University of California, San Diego School of Medicine and the Ludwig Institute for Cancer Research have discovered a novel pathway activated by ...

New method increases supply of embryonic stem cells

A new method allows for large-scale generation of human embryonic stem cells of high clinical quality. It also allows for production of such cells without destroying any human embryos. The discovery is a big step forward ...

'Cowcatcher' enzyme fixes single-strand DNA

Every time one of your cells divides, it exposes its most essential component to great danger: its genome, the sum total of all its genetic information, embodied in the double-stranded helix of DNA. Prior to cell division, ...

Computer models shed new light on sickle cell crisis (w/ video)

Using powerful computer models, researchers from Brown University have shown for the first time how different types of red blood cells interact to cause sickle cell crisis, a dangerous blockage of blood flow in capillaries ...

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