'Cowcatcher' enzyme fixes single-strand DNA

Every time one of your cells divides, it exposes its most essential component to great danger: its genome, the sum total of all its genetic information, embodied in the double-stranded helix of DNA. Prior to cell division, ...

Taking the fight into the enemy's territory

(Phys.org) —German researchers have developed a scheme for the preparation of nanoparticles that offer a highly versatile system for targeted drug delivery directly into diverse types of tumor cells.

Computer models shed new light on sickle cell crisis (w/ video)

Using powerful computer models, researchers from Brown University have shown for the first time how different types of red blood cells interact to cause sickle cell crisis, a dangerous blockage of blood flow in capillaries ...

Scientists discover how mitochondria import antioxidants

Many of the processes that keep us alive also put us at risk. The energy-producing chemical reactions in our cells, for example, also produce free radicals—unstable molecules that steal electrons from other molecules. When ...

Researchers clarify how DNA damage signaling works

The DNA molecule is chemically unstable, giving rise to DNA lesions of various kinds. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed. The DNA damage response ...

Nanoparticles may cause DNA damage across a cellular barrier

(PhysOrg.com) -- Scientists have shown in the laboratory that metal nanoparticles damaged the DNA in cells on the other side of a cellular barrier. The research, by the University of Bristol, is published online this week ...

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