Cryo-EM reveals how '911' molecule helps fix damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.

Developing tools to visualize DNA repair as never before

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects ...

Scientists discover how mitochondria import antioxidants

Many of the processes that keep us alive also put us at risk. The energy-producing chemical reactions in our cells, for example, also produce free radicals—unstable molecules that steal electrons from other molecules. When ...

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