Chlamydia promotes gene mutations

Chlamydia trachomatis is a human pathogen that is the leading cause of bacterial sexually transmitted disease worldwide with more than 90 million new cases of genital infections occurring each year. About 70 percent of women ...

DNA damage: The dark side of respiration

(Phys.org) —Adventitious changes in cellular DNA can endanger the whole organism, as they may lead to life-threatening illnesses like cancer. Researchers at LMU now report how byproducts of respiration cause mispairing ...

Protein maintains order in the nucleus

Researchers in Freiburg identify a protein responsible for the correct arrangement of the chromosome centromeres in the nucleus.

Hereditary neurodegeneration linked to ADP-ribose modification

Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...

Silver nanoparticles may adversely affect environment

In experiments mimicking a natural environment, Duke University researchers have demonstrated that the silver nanoparticles used in many consumer products can have an adverse effect on plants and microorganisms.

Stem cells: Tuning the death sentence

In this week's issue of Science Signaling (22 January, 2013), Danen and colleagues of the Division of Toxicology of LACDR report novel insights into the question how stem cells decide to commit suicide when their DNA is damaged.

Some cells don't know when to stop

Certain mutated cells keep trying to replicate their DNA—with disastrous results—even after medications rob them of the raw materials to do so, according to new research from USC.

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