New understanding of gating mechanism of CFTR chloride channel

New research advances our understanding of the gating mechanism of the CFTR, the chloride channel mutated in cystic fibrosis patients. The study by Tzyh-Chang Hwang and colleagues (University of Missouri), and accompanying ...

Bacterial colonization of the lung also depends on the host genome

The lung is by no means a sterile place, as was assumed for a long time. In fact, it actually harbors a diverse microbial ecosystem. We know from previous studies that changes in the lung microbiome are associated with diseases ...

How cells export and embed proteins in the membrane

Like an overprotective parent on the first day of school, a targeting factor sometimes needs a little push to let go of its cargo. Scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have visualised ...

Researchers discover new ways to treat chronic infections

Researchers at Binghamton University, State University of New York, have identified three key regulators required for the formation and development of biofilms. The discovery could lead to new ways of treating chronic infections.

Researchers use bacterial communication as a target for new drugs

The pathogen Pseudomonas aeruginosa is the cause of a large number of serious infections and places a particular burden on immunocompromised patients. The increasing spread of antimicrobial resistance makes it even more difficult ...

Stripping away an infection's armour

A Massey professor of microbiology has identified a protein that could help fight serious infections in elderly, cancer, HIV and cystic fibrosis patients.

Bacteria 'launch a shield' to resist attack

Bacteria that cause chronic lung infections can communicate with each other to form a deadly shield against the body's natural defenses. Studying these interactions could lead to new ways of treating bacteria that are resistant ...

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