Study finds 'silent' genetic variations can alter protein folding

Proteins, the workhorse of the human cell, help digest our food, carry oxygen through the body, fight off invading microbes, and so much more—but they only function when folded properly into specific, three dimensional ...

Research team tackles superbug infections with novel therapy

There may be a solution on the horizon to combating superbug infections resistant to antibiotics. The tenacious bacteria and fungi sicken more than 2.8 million people and lead to more than 35,000 deaths in the United States ...

Curing genetic disease in human cells

While the genome editing tool CRISPR/Cas9, developed in 2012, cuts a mutation out of a gene and replaces it with a gene-piece, a newer type of CRISPR, called base-editing, can repair a mutation without cutting the DNA. Therefore, ...

New agents to fight multidrug-resistant germs

Resistance to antibiotics is on the rise worldwide. Fraunhofer scientists have joined forces with partners in the Phage4Cure project to explore alternatives to antibiotics. One objective is to vanquish multidrug-resistant ...

Determining what binds to mucus

The human body is full of mucus. This viscous goo isn't just a nuisance that gets coughed up or sneezed out—it can bind to drugs, toxins or microbes, potentially impacting human health. However, relatively little is known ...

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