How HIV smuggles its genetic material into the cell nucleus

Each year, about 1 million individuals worldwide become infected with HIV, the virus that causes AIDS. To replicate and spread the infection, the virus must smuggle its genetic material into the cell nucleus and integrate ...

Research group describes how cilia's motor works

Using cryo-electron tomography, researchers have uncovered details of how the dynein motor protein drives cilia to beat. Understanding this motion may help to tackle health problems that affect cilia, which range from fertility ...

3-D model shows bacterial motor in action

Nagoya University scientists in Japan and colleagues at Yale University in the US have uncovered details of how the bacterial propeller, known as the flagellum, switches between counterclockwise and clockwise rotation, allowing ...

Microscopic chariots deliver molecules within our cells

On the cellular highway, motor proteins called dyneins rule the road. Dyneins "walk" along structures called microtubules to deliver cellular cargo, such as signaling molecules and organelles, to different parts of a cell. ...

Method speeds up time to analyze complex microscopic images

Cryo-electron tomography permits researchers to study in detail the microscopic structures inside of cells. Researchers who typically required a week of effort to dissect the 3-D structure of a single cell will now be able ...

Scientists illuminate structures vital to virus replication

In the fight against the viruses that invade everyday life, seeing and understanding the battleground is essential. Scientists at the Morgridge Institute for Research have, for the first time, imaged molecular structures ...

Research team captures images of pathogens' tiny 'syringes'

Salmonella and many other bacterial pathogens use a nano syringe-like device to deliver toxic proteins into target human cells. Now scientists at Yale and University of Texas Medical School-Houston have used cryo-electron ...

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