An important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes, according to a new study by researchers ...
Biotechnology
Dec 1, 2021
0
18
Researchers at Massachusetts General Hospital (MGH) have uncovered new clues that add to the growing understanding of how female mammals, including humans, 'silence' one X chromosome. Their new study, published in Molecular ...
Cell & Microbiology
Mar 15, 2021
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29
Researchers at Massachusetts General Hospital (MGH) have solved a mystery that has long puzzled scientists: How do the bodies of female humans and all other mammals decide which of the two X chromosomes it carries in each ...
Cell & Microbiology
Aug 17, 2020
6
344
Biomedical scientists at KU Leuven have unraveled parts of a mechanism that may one day help to treat Rett syndrome and other genetic disorders linked to the X chromosome.
Biotechnology
Sep 12, 2019
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42
As many know, females have two X chromosome while males have one X and one Y chromosome.
Cell & Microbiology
Feb 20, 2019
0
88
Autoimmune diseases tend to strike women more than men and having multiple X chromosomes could be the main reason why. While a process called X chromosome inactivation serves to balance out gene dosage between males and females, ...
Biotechnology
Oct 19, 2017
0
162
The addition of a chemical tag on an RNA molecule is the critical switch that inactivates one X chromosome in every cell, ensuring healthy development in all female mammals, according to new research by Weill Cornell Medicine ...
Biotechnology
Sep 19, 2016
0
23
Researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. By studying an important lncRNA, called Xist, the scientists identified ...
Biotechnology
Apr 27, 2015
1
76
Established human embryonic cell lines, including those approved for federal research funding under former President George W. Bush, are different than newly derived human embryonic stem cell lines, according to a study by ...
Cell & Microbiology
Dec 1, 2011
0
0
Oxygen levels in the lab can permanently alter human embryonic stem (ES) cells, specifically inducing X chromosome inactivation in female cells, according to Whitehead Institute researchers. Human ES cells have been routinely ...
Cell & Microbiology
May 13, 2010
0
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