Decoding the cell's genetic filing system

A fully extended strand of human DNA measures about five feet in length. Yet it occupies a space just one-tenth of a cell by wrapping itself around histones—spool-like proteins—to form a dense hub of information called ...

Highly sensitive epigenomic technology combats disease

Much remains unknown about diseases and the way our bodies respond to them, in part because the human genome is the complete DNA assembly that makes each person unique. A Virginia Tech professor and his team of researchers ...

FloChiP, a new tool optimizing gene-regulation studies

In the cell, proteins often interact directly with DNA to regulate and influence the expression of genes. For this to happen, proteins need to travel into the cell's nucleus where the DNA is tightly twisted and packed as ...

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