Engineering enzymes to perform reactions not found in nature can address longstanding challenges in the world of synthetic chemistry, such as upgrading plant-based oils into useful biochemicals.
Biochemistry
May 2, 2022
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77
Scientists at the University of Southampton have discovered a new way to create one hand of a chiral molecule by using a mechanical bond as a catalyst.
Materials Science
Mar 9, 2020
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17
Breaking carbon-hydrogen (C-H) bonds to alter existing molecules to create new ones is an increasingly important avenue for drug development. Of particular interest is mirror-image or "one-handed" compounds, but C-H breaking ...
Materials Science
Oct 23, 2014
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0
Chemists at Scripps Research have addressed one of the most formidable challenges in synthetic chemistry by inventing a method for "enantioselective remote meta-CH activation," which enables the making of chiral molecules ...
Materials Science
Jun 18, 2018
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43
Physicists at the University of Bath have devised a new and highly sensitive method to truly test the chirality of a material, eliminating the risk of false positives from competing effects.
Nanophysics
Jun 26, 2018
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12
The hunt for the organic molecules that create proteins and enzymes critical for life here on Earth has largely happened in sophisticated terrestrial laboratories equipped with high-tech gadgetry needed to tease out their ...
Space Exploration
Nov 16, 2012
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0
The concept of chirality is well-established in science: when an object cannot be superimposed on its mirror image, both the object and its mirror image are called chiral. In the drug industry, for instance, more than 50% ...
Quantum Physics
Jun 22, 2020
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209
You can get a good idea of chirality by putting a right-handed glove on your left hand—two identical shapes that cannot be superimposed because they are mirror images of each other. This property is common in our universe, ...
Materials Science
Dec 8, 2017
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7
Imagine trying to build a Colosseum-type edifice—including arches, vaults and various protrusions—while abiding by two strict rules: Only one type of brick may be used, and these bricks are required to be placed precisely, ...
Materials Science
Jun 30, 2020
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58
Did you know that more than half of the drugs currently in use are chiral, potentially resulting in two different responses in the body? Chiral compounds are pairs of molecules that are mirror images of each other, just like ...
Materials Science
Feb 21, 2019
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6
